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KMID : 0359920100290010104
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Korean Journal of Nephrology
2010 Volume.29 No. 1 p.104 ~ p.109
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Three Cases of Minimal Change Nephrotic Syndrome in Patients with Type 2 Diabetes
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Jeon Jun-Seok
Lee Jung-Eun
Lee Jin-Hee
Jeong Byeong-Ho
Cho Ah-Jin
Kwon Gee-Young
Huh Woo-Sung
Kim Yoon-Goo
Kim Dae-Joong
Oh Ha-Young
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Abstract
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Diabetic nephropathy is a common and serious complication of diabetes characterized by persistent proteinuria, hypertension and a progressive decline of renal function. However, non-diabetic renal disease can be present in diabetic patients and differential diagnosis of treatable disease is important.Minimal change nephrotic syndrome is characterized by normal light microscopic finding and effacement of foot process in electron microscope, but foot process effacement is not specific and it can be present in the glomeruli of the most glomerulopathy including diabetic nephropathy. Therefore, pathNephrotic syndrome, minimal change, Type 2 diabetes mellitus, Corticosteroid ologic diagnosis of minimal change nephrotic syndrome combined with diabetic nephropathy is very difficult.However, we could exclude other glomerulopathy and diagnose minimal change nephrotic syndrome by clinical features in three type 2 diabetic patients with diabetic nephropathy and have successfully treated with corticosteroid.
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KEYWORD
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Nephrotic syndrome, minimal change, Type 2 diabetes mellitus, Corticosteroid
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